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There are so many other factors that influence our likelihood of contracting any given disease, and many of them are outside our control. But one that we definitely do have some power over is that of our mindset. I think there’s a lot to be said for the ability of a strong and determined (positive) mind. It’s amazing how people who put a negative spin on everything seem to be so much more plagued by all manner of illness. I’m not saying that a happy or positive person can’t get sick, but it is a possible contributing factor, and certainly one worth giving a go anyway!

Learning to be happy and positive is just like creating any other habit – it takes time and deliberate attention. A good starting point is to become more aware of your thought patterns, and deliberately try to turn around those internal negative responses.

Sorry, have gone way off on a tangent here!

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@ HMama – Yes CR is not the most appealing name, and most that do practice it are also very very skinny (probably more than what most people who also want some muscle are willing to do). But eating less can be beneficial at some level.

@Yavor – Good rules (even if I do eat less during the day and more at night…there is always more than one way to be healthy and happy!)

@James – Autophagy is an ongoing process that declines with age, it doesn’t really turn on or off. But you can “increase” function, which can help people more as they age (not really with younger people who are already running at peak capacity). There has to be a “low food” stress to signal an increase so it starts “consuming itself” at the cell level for energy (and in some cases exercise may do this as well). I’ve read that this is also dependent on one’s bodyfat, because as you fast your body turns to fat for energy. So if you have more fat stored, you are still not signaling enough of a “low food” environment compared to someone who is lower in bodyfat. CR studies are low calories over longer periods of time, compared with IF. So in a sense there is no “magic” number for when does fasting “maximize” autophagy (but maybe more research will be done in the future to determine it). So does one 24 hr fast really signal a large increase in autophagy compared to a 18hr fast? Possibly as it makes sense the longer a fast then the more of a low food stimulus you would create. Does a 3 day fast do more healing? Possibly. Would people with existing conditions need longer low calorie time frames for benefit (like when you hear about people with cancers being treated with weeks of juice fasting)? Possibly again. What about comparing a single 24 hr fast to a daily 18hr fast over time? That I have no information on, but I would like to know as well. Also when talking about the more frequent shorter IF windows you would have to look at the whole calorie load over time and if it is promoting enough of a “low food” stress like CR would. I am really excited to see autophagy getting more and more attention, so hopefully more research will come about from it. research and studies on CR and IF over time. I would love to see more of this type of research being applied into more traditional modern treatments for diseases to help increase repair and recovery. Sorry I went off rambling, but there is more exciting stuff with autophagy on the horizon I have a feeling…..

@Greg – Eating excess calories all the time is still not a great idea, especially as we get older. Excess calories can lead to more oxidation, more free radicals, more wear and tear, downturn of cellular recycling and all that good stuff. Doing short cycles for adding more muscle won’t probably make a huge difference, it’s going to be how is it maintained over the long run. The smartest BB types I know also use cycles of low calories and don’t eat too much to excess otherwise.

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Thanks for your hard work here, it is very much appreciated .

James

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1. Avoid trans fats/hydrogenated fats/margarine etc.

2. Treat desert as desert and not as the main meal.

3. Eat less.

4. Follow the rule – eat breakfast like a king, lunch like a prince and dinner like a pauper.

5. Move, train and play.

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